Guillermo Rigondeaux
Among the current active fighters I would say it's either Floyd Mayweather or Bernard Hopkins. It's natural pedigree for Floyd and natural fighting knack and smart for BHop which he discovered on the rowdy streets of Philadelpia and in his prison stint.
Rigondeaux, Manny or Lomachenko.
Of all time - Roy Jones Jr
Mayweather, Pacquaio, and golovkin
Just asking for people's opinions, not looking to get into a debate about natural talent vs hard work, or something along those lines.