Yes, and not just with an uppercut but a hook or a cross but probably not with just a jab
Probably unless the woman was pretty weak or the man had a good chin either way KO or no KO the woman would probably fracture or break her hand, that's why they use gloves in boxing and mma.
if she's a actual real Fighter say cris cyborg or ann wolfe or somebody and he's not a fighter then hell yeah..
yeah probably unless he's got an awesome chin
If the man lets her hit him with all she's got. If both are healthy and athletic. They are both average size.
